abstract：BACKGROUND/AIMS:Increasing evidence suggests that clinical signs of periodontal disease are independently associated with renal impairment. However, no studies have examined the possible linkage of kidney disease with serum antibody to oral pathogens. METHODS:The periodontal disease status was assessed in an older com...

journal_title：Blood purification

authors： Kshirsagar AV,Offenbacher S,Moss KL,Barros SP,Beck JD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic kidney disease (CKD) and periodontitis (PD) are serious public-health concerns. Vitamin D is a fat-soluble steroid hormone that interacts with its nuclear receptor (VDR) to regulate a variety of biological processes, such as bone metabolism, immune response modulation and transcription of severa...

journal_title：Blood purification

authors： de Souza CM,Braosi AP,Luczyszyn SM,Avila AR,de Brito RB Jr,Ignácio SA,Probst CM,Riella MC,Sotomaior VS,Mira MT,Pecoits-Filho R,Trevilatto PC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:To study calcium homeostasis during citrate-based compared to nadroparin-based CVVH in critically-ill patients with acute renal failure. METHODS:11 patients were observed during citrate anticoagulation, 9 with nadroparin and 10 controls. Citrate was chosen for patients with active or at risk for bleeding. ...

journal_title：Blood purification

authors： van der Voort PH,Postma SR,Kingma WP,Boerma EC,de Heide LJ,Bakker AJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The mortality rate of peritoneal dialysis (PD) patients is still high and controversies persist regarding the mortality predictor. This study was designed to identify the predictability of the extracellular water/intracellular water ratio (E/I) on mortality in PD patients. METHODS:227 incident PD patients w...

journal_title：Blood purification

authors： Chen W,Guo LJ,Wang T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Establishment of reference values for small solute transport, sodium sieving and effluent CA125 with 3.86% (4 h) peritoneal equilibration test (PET), and comparison with fast-fast PET with regard to small solute transport categories. METHODS:Cross-sectional study; 69 prevalent patients. Sodium sieving ...

journal_title：Blood purification

authors： Rodrigues AS,Silva S,Bravo F,Oliveira JC,Fonseca I,Cabrita A,Krediet RT

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) levels are increased in hemodialysis (HD) patients. Reports on the effect of various dialysis strategies on ADMA, symmetric dimethylarginine (SDMA) and L-arginine levels are inconclusive. PATIENTS/METHODS:In this randomized crossover study, 15 patients were dialyzed for 4 ...

journal_title：Blood purification

authors： Grooteman MP,Wauters IM,Teerlink T,Twisk JW,Nubé MJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIM:Haemodialysis-treated patients are at a high risk of developing cardiovascular disease. Part of this risk may be attributable to the type of the dialysis membrane used. We evaluated whether different dialysis membranes differ with respect to platelet activation. METHODS:In a randomized crossover trial, ...

journal_title：Blood purification

authors： Thijs A,Grooteman MP,Zweegman S,Nubé MJ,Huijgens PC,Stehouwer CD

更新日期：2007-01-01 00:00:00

abstract：:Endothelial dysfunction of the optic microcirculation is considered to be the main pathogenetic mechanism in nonarteritic ischemic optic neuropathy. The aim of the present work was to assess whether a clinical improvement is correlated with a reduction in the endothelial activation markers by means of LDL apheresis (L...

journal_title：Blood purification

authors： Ramunni A,Ranieri G,Giancipoli G,Guerriero S,Ria R,Saliani MT,Sborgia L,Ranieri P,Coratelli P

更新日期：2006-01-01 00:00:00

abstract：:The biological processes governing vascular endothelial cell health are complex and highly redundant. The mechanisms involved in cell injury and repair remain an area of intense study. This paper attempts to review current knowledge regarding hormones such as vitamin D, erythropoietin and aldosterone within the contex...

journal_title：Blood purification

authors： Levin A

更新日期：2006-01-01 00:00:00

abstract：:There is a wide variability in the utilization of peritoneal dialysis throughout Europe that cannot be explained by differences in medical factors alone. Over the last years, the utilization of peritoneal dialysis has even changed in individual countries. The main factors of this variation are not medical, but rather ...

journal_title：Blood purification

authors： Lameire N,Peeters P,Vanholder R,Van Biesen W

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Dialysis patients have higher cardiovascular events rate than patients with normal renal function. Hyperhomocysteinemia, a risk factor for cardiovascular disease, is frequently detected in dialysis patients. Vitamin B supplementation lowers hyperhomocysteinemia, but it is unknown whether it reduces cardiovas...

journal_title：Blood purification

authors： Righetti M,Serbelloni P,Milani S,Ferrario G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6) levels is also characteristic of end-stage renal disease. This study investigates the effects of intravenous calcitriol on serum bone resorptive ...

journal_title：Blood purification

authors： Lu KC,Tseng CF,Wu CC,Yeung LK,Chen JS,Chao TY,Janckila AJ,Yam LT,Chu P

更新日期：2006-01-01 00:00:00

abstract：:The effects of pulsatile perfusion on microcirculation and renal function in high-risk patients were evaluated in this study. Pulsatile roller pumps with a pulsatile control module and membrane oxygenator were used in a clinical setting. 40 patients undergoing elective cardiac surgery with a high risk of either having...

journal_title：Blood purification

authors： Kocakulak M,Aşkin G,Kuçukaksu S,Tarcan O,Pişkin E

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a clear association between one allele of the interleukin-1 receptor-antagonist gene (IL-1RN) and inflammatory diseases in which IL-1 is implicated. We evaluated patient survival and technique survival of peritoneal dialysis (PD) patients, while analyzing independent risk factors, in a PD progr...

journal_title：Blood purification

authors： Uchiyama K,Naito K,Tsuchida M,Takai K,Okayama N,Fujimura K,Hinoda Y

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:We explored whether biocompatible dialyzer membranes modulate the inflammatory response during blood contact in patients with systemic inflammation. METHODS:15 patients with end-stage renal disease and systemic inflammation (mean serum C-reactive protein 86 +/- 4 mg/l) were randomly treated with Cuprophan (...

journal_title：Blood purification

authors： Gueler F,Gwinner W,Schiborr C,Martin M,Klos A,Kirsch T,Fiebeler A,Haller H,Fliser D

更新日期：2005-01-01 00:00:00

abstract：:The recent recognition that hyperphosphatemia is a strong predictor of survival on dialysis has rekindled interest in the regulation and control of serum phosphate. In incipient renal failure hyperphosphatemia is prevented by increased fractional renal phosphate excretion mediated via an increase in parathyroid hormon...

journal_title：Blood purification

authors： Ritz E,Gross ML

更新日期：2005-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) remains the major cause of morbidity and mortality in end-stage renal disease (ESRD) patients. As traditional risk factors cannot alone explain the unacceptable high prevalence and incidence of CVD in this population, inflammation (a common phenomenon in ESRD), and other non-traditional ri...

journal_title：Blood purification

authors： Stenvinkel P,Lindholm B

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Glucose absorbed from conventional peritoneal dialysis (PD) solutions contributes to unfavorable metabolic effects. Its replacement with a glucose-free osmotic agent such as icodextrin (ID) or amino acids (AA) may have some benefit on glucose and lipid metabolism. METHODS:Serum lipids, insulin sensitivity a...

journal_title：Blood purification

authors： Martikainen T,Teppo AM,Gronhagen-Riska C,Ekstrand A

更新日期：2005-01-01 00:00:00

abstract：:A strict control of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) is indicated to avoid serious complications linked to osteitis fibrosa and other parathyroid-hormone (PTH)-related bodily disturbances. However, such a control is often achieved only at the price of unacceptably high plasma...

journal_title：Blood purification

authors： Drüeke TB

更新日期：2004-01-01 00:00:00

abstract：:Dialysis fluid produced by state-of-the-art water preparation and distribution is contaminated with gram-negative bacteria and cytokine-inducing substances (CIS) derived from these microorganisms. The presence of a biofilm increases the risk of continuous contamination of dialysis fluid. Depending on the type of dialy...

journal_title：Blood purification

authors： Lonnemann G

更新日期：2004-01-01 00:00:00

abstract：:During the past few years, it has become increasingly evident that residual renal function (RRF) is an important and independent predictor of poor outcome in patients with chronic kidney disease (CKD). Although the causes of this observation are not fully understood, it appears that the loss of RRF impairs both fluid ...

journal_title：Blood purification

authors： Pecoits-Filho R,Gonçalves S,Barberato SH,Bignelli A,Lindholm B,Riella MC,Stenvinkel P

更新日期：2004-01-01 00:00:00

abstract：:The greatest benefit of PD ist the continuous maintenance of a stable electrolyte and acid-base balance, as well as a continuous solute, sodium and water removal. Moreover, PD is effective in preserving residual renal function (RRF). However, when RRF declines, complications will occur if not compensated for by an inc...

journal_title：Blood purification

authors： Kawanishi H

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:We have reported that vitamin D deficiency may be implicated in the pathogenesis of hypoalbuminemia observed in patients with end-stage renal disease, but the mechanism remains to be clarified. The aim of the present study was to determine whether supplementation with alfacalcidol might increase protein inta...

journal_title：Blood purification

authors： Yonemura K,Sugiura T,Yamashita F,Matsushima H,Hishida A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:Sudden K removal is thought to be implicated in ECG alterations observed during hemodialysis (HD). The effects of the K removal rate on ECG-derived parameters have been investigated. METHODS:Two different hemodiafiltration (HDF) schedules were used for 10 HD patients: the dialysate K concentration was ...

journal_title：Blood purification

authors： Severi S,Vecchietti S,Cavalcanti S,Mancini E,Santoro A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study evaluated the mechanism of hemodynamic improvement in polymyxin B-immobilized fiber (PMX) treatment. METHODS:Fifteen septic patients with endotoxemia and/or gram negative infection were treated with PMX. Plasma concentrations of calcitonin gene-related peptide (CGRP) and nitric oxide metabol...

journal_title：Blood purification

authors： Shimizu T,Hanasawa K,Tani T,Endo Y,Kurumi Y,Ikeda T,Fujita N,Morita H,Imaizumi H,Sato T,Katayama H

更新日期：2003-01-01 00:00:00

abstract：:The recent Kidney Disease Outcomes Quality Initiative (K/DOQI) classification of chronic kidney disease (CKD) includes transplant recipients. Although there are important differences between kidney transplant recipients (KTRs) and patients with native kidney disease, the inclusion of KTRs along with other CKD patients...

journal_title：Blood purification

authors： Gill JS,Pereira BJ

更新日期：2003-01-01 00:00:00

abstract：AIMS:To study incidence, clinical features, and outcome of critically ill patients with end-stage renal failure (ESRF) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) and to test the validity of severity scoring systems for these patients. METHODS:Data for ESRF patients treated with RRT were...

journal_title：Blood purification

authors： Uchino S,Morimatsu H,Bellomo R,Silvester W,Cole L

更新日期：2003-01-01 00:00:00

abstract：:Doubt has remained as to whether or not the K/DOQI recommended targets for adequacy of dialysis for peritoneal dialysis patients is appropriate (weekly Kt/V 2 + creatinine clearance 50-60 l/1.73 m(2)). The ADEMEX trial can be interpreted as indicating that lower targets might be acceptable. The HEMO trial, not yet pub...

journal_title：Blood purification

authors： Prichard S

更新日期：2003-01-01 00:00:00

abstract：:Uremic patients suffer from a secondary form of complex dyslipidemia consisting of quantitative and qualitative abnormalities in serum lipoproteins resulting in altered lipoprotein composition and metabolism. The most prominent are an increase in serum triglyceride levels (due to elevated very-low-density lipoprotein ...

journal_title：Blood purification

authors： Wanner C,Krane V

更新日期：2002-01-01 00:00:00

abstract：:A review is given of the conditions associated with peritoneal membrane failure, and the possible causes. Ultrafiltration failure is the most important manifestation. It is mostly associated with high transport rates of low molecular weight solutes suggesting the presence of a large vascular surface area. Enlargement ...

journal_title：Blood purification

authors： Krediet RT,Van Esch S,Smit W,Michels WM,Zweers MM,Ho-Dac-Pannekeet MM,Struijk DG

更新日期：2002-01-01 00:00:00

abstract：:The administration of intravenous fluids is perhaps the most common treatment given in the intensive care unit. According to biologic rationale, ongoing fluid losses should be replaced to maintain fluid homeostasis and relative or absolute deficiencies in circulating blood volume should be prevented or rapidly correct...

journal_title：Blood purification

authors： Bellomo R

更新日期：2002-01-01 00:00:00

abstract：:We report the clinical course of 29 patients with Wegener's granulomatosis (WG) treated with plasma exchange (PE) in Norway in the period from 1988 to 1999. Median follow-up was 41.5 months. The mean number of exchanges was 8.5 +/- 5.8 (range 2-32). Median serum creatinine concentration was 400 micromol/l (range 90-1,...

journal_title：Blood purification

authors： Aasarød K,Iversen BM,Hammerstrøm J,Bostad L,Jørstad S

更新日期：2002-01-01 00:00:00

abstract：:The mortality from sepsis complicated by renal failure remains extremely high despite the application of modern renal replacement therapy. This study investigated whether treatment with a bioartificial kidney consisting of a hemofilter in a continuous venovenous hemofiltration circuit (CVVH) with a cartridge containin...

journal_title：Blood purification

authors： Fissell WH,Dyke DB,Weitzel WF,Buffington DA,Westover AJ,MacKay SM,Gutierrez JM,Humes HD

更新日期：2002-01-01 00:00:00

abstract：:At present the treatment of hepatitis C virus infection (HCV) has improved because of combined treatment with interferon (IFN) and ribavirin. The association of these two drugs has obtained a positive response in 40-50% of naive patients treated. Patients with relapse after monotherapy with IFN also show positive resp...

journal_title：Blood purification

authors： Sánchez Tapias JM,Rodés J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Interleukin-10 (IL-10), a potent regulatory monokine produced by activated mononuclear cells, provides an efficient autocrine mechanism for controlling proinflammatory cytokine synthesis. We hypothesized that defective synthesis of IL-10 could contribute to the inflammatory state in hemodialysis (HD) patient...

journal_title：Blood purification

authors： Perianayagam MC,Jaber BL,Guo D,King AJ,Pereira BJ,Balakrishnan VS

更新日期：2002-01-01 00:00:00

abstract：:Elimination of uremic solutes with molecular weights up to 60 kD, without significant loss of albumin is an important therapeutic goal to optimize outcomes in chronic hemodialysis patients. To characterize a newly developed polysulfone dialyzer (APS-650) a comparative analysis was performed with a highly advanced poly...

journal_title：Blood purification

authors： Klingel R,Ahrenholz P,Schwarting A,Röckel A

更新日期：2002-01-01 00:00:00

abstract：:Contradictory data are reported in the literature concerning the diffusion kinetics of inorganic phosphates (iPh) between red blood cells and plasma during haemodialysis. Accordingly, we performed mass balance and equilibration studies to analyze the diffusion kinetics of iPh in vivo and in vitro. Mass balance analysi...

journal_title：Blood purification

authors： Descombes E,Jutzet A,Perriard F,Fellay G

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Hemodiafiltration (HDF) is effective in delaying the surgical need for carpal tunnel syndrome in chronic hemodialysis patients, however, predialysis beta(2)-microglobulin levels were not reduced in most short-term studies. The aim of this study was to assess the effect of long-term and differing frequencies ...

journal_title：Blood purification

authors： Lin CL,Yang CW,Chiang CC,Chang CT,Huang CC

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED:Hyperhomocysteinemia (HH), a known risk factor for vascular diseases, is a frequent condition in hemodialysis (HD) patients. HH induces an oxidant stress to the vascular endothelium, causing a failure of vasodilation and an impairment of the antithrombotic properties. Vitamins B(6), B(12) and folic acid are ...

journal_title：Blood purification

authors： Biasioli S,Schiavon R

更新日期：2000-01-01 00:00:00

abstract：:Plasma exchange (PE) is an effective therapeutic method used in patients with myasthenia gravis (MG) refractory to common therapy and/or with life-threatening respiratory complications. Except for acetylcholine receptor antibodies (AChRAbs), some other inflammatory mediators possibly activated in MG may also be remove...

journal_title：Blood purification

authors： Tesar V,Jelínková E,Jirsa M Jr,Bakosová M,Pitha P,Chábová V

更新日期：2000-01-01 00:00:00